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FLASH GENE
Symbol RNASE4 contributors: nmct - updated : 18-07-2008
HGNC name ribonuclease, RNase A family, 4
HGNC id 10047
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • polypeptide with eight cysteine, histidine and lysine residues
    • HOMOLOGY
    Homologene
    FAMILY
  • ribonuclease, RNAse A family
  • pancreatic ribonuclease family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides
  • maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS