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FLASH GENE

Symbol

MLX

contributors: - updated : 27-04-2006

HGNC name	MAX-like protein X
HGNC id	11645

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	basic helix-loop-helix (HLH)
	leucine zipper domains

mono polymer

homomer , heteromer , dimer

HOMOLOGY

Homologene

FAMILY	basic helix-loop-helix (BHLH) family of transcription factors
	BHLH-ZIP subfamily

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION

basic FUNCTION

repressing transcription by recruiting the Sin3A-histone deacetylase corepressor complex

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

text	transcription repressor

PATHWAY

metabolism

signaling

a component	heterodimerize with MAD1,MAD4,MNT and WBSCR14
	homodimerize

INTERACTION

DNA	binding to 5'-CACGTG-3'

RNA

small molecule

protein	MAD1
	MAD4
	MNT
	WBSCR14
	MLXIP

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS