basic FUNCTION
| acting as microtubule-based anterograde translocator for membranous organelles |
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playing a role in various intracellular transport and spindle formation |
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KIF3B mutant photoreceptor cilia differentiate with a delay, suggesting that KIF3C, although redundant with KIF3B at later stages of differentiation, is not active early in photoreceptor ciliogenesis |
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is a key regulator of axonal growth and regeneration by controlling microtubule dynamics and organization in the growth cone |
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KIF3C is an injury-specific kinesin that contributes to axon growth and regeneration by regulating and organizing the microtubule cytoskeleton in the growth cone |
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functions as a motor protein involved in axonal transport in neuronal cells |
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KIF3A, KIF3B, KIF3C is classified as a heterotrimeric kinesin-2 that is best known for organelle transport in neurons |