basic FUNCTION
| involved in hair formation and spermatogenesis |
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involved in the differentiation and/or maintenance of the urogenital system |
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negatively regulates its own expression by binding to and repressing the activity of its promoter |
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restricts its own expression by counteracting c-Myb activation and histone acetylation of the OVOL1 promoter |
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required for multiple developmental processes, including that of epidermis, hair follicles, kidney, and male germ cell differentiation |
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promotes the transition of cells from a proliferating, less-differentiated state to a quiescent more-differentiated state and may play an important role in regulating the balance between proliferation and differentiation of pancreatic cells |
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repressor of MYC transcription that regulates keratinocyte exit from the cell cycle and induction of differentiation |
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OVOL1, OVOL2 are gatekeepers of epithelial adhesion and differentiation by inhibiting progenitor-like traits and epithelial plasticity |
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regulates the transition from progenitor to differentiated trophoblast cell |
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important function of OVOL1 as a regulator of trophoblast progenitor cell fate during human trophoblast development |