protein
| myogenic differentiation 1, MyoD1 ( |
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Id1, Id2, and Id3 ( |
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fibroblast growth factor (FGF)-1 promoter, FGF-1.B ( |
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calmodulin ( |
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HASH1 ( |
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Id4 ( |
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beta-catenin, CTNNB ( |
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Math1 ( |
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menin ( |
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CDX2 |
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FGFR3 |
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ZEB1 is an effector of CTNNB1/TCF4 signaling in epithelial-to-mesenchymal transition and tumor progression |
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FAM96B is an interaction partner of TCF4 |
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binds to E-box DNA sequences (CANNTG) |
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SOX9 regulates LRP6, TCF4 expression and WNT/CTNNB1 activation in breast cancer |
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AGBL1 interacts biochemically with the FCD (Fuchs corneal dystrophy) -associated protein TCF4 and the mutations found in our cohort of FCD individuals diminish this interaction |
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PLAGL1 interacts with TCF4, and PLAGL1 and TCF4 expression concomitantly increased during neuronal progenitor differentiation |
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WNT1 regulates the expression of CD36 through TCF4 and PPARG |
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suppresses angiogenesis after ischemic injury and impairs Wnt/CTNNB1 signaling by disrupting the interaction between CTNNB1 and TCF4 |
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SPINDOC associates with TCF4 in a SPIN1-dependent manner and dampens SPIN1 coactivator activity |
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ZNF433 enhanced the binding between CTNNB1 and TCF4 |
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KIFC1, activated by TCF4, functions as an oncogene and promotes HCC pathogenesis through regulating HMGA1 transcriptional activity |
Variant & Polymorphism
SNP
, repeat
| very enlarged CTG alleles maybe associated to bipolar disorder |
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a marker in intron 4 specifically associated to schizophrenia |
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region of hemizygosity including TCF4, NETO1, and FBXO15 significantly more likely to exhibit autistic-like behaviors |
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rs17089887 and rs17089925 strongly associated with Fuchs' corneal dystrophy ( |
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association of TCF4 (rs613872, rs9954153, rs2286812 )wih Fuchs' corneal dystrophy |
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