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FLASH GENE
Symbol CORT contributors: mct - updated : 19-06-2009
HGNC name cortistatin
HGNC id 2257
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 21 AA putative signal sequence
  • HOMOLOGY
    interspecies homolog to murine Cort
    intraspecies homolog to somatostatin,highly
    Homologene
    FAMILY
  • somatostatin family
  • CATEGORY signaling neurotransmitter , receptor membrane G
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • involved in synaptic transmission
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding SSTR1, SSTR2, SSTR3, SSTR4, SSTR5, as well the GH secretagogue (GHS)/ghrelin receptors
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional     --low  
    in patients with proliferative diabetic retinopathy
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS