Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol MAT1A contributors: npt - updated : 23-09-2004
HGNC name methionine adenosyltransferase I, alpha
HGNC id 6903
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , tetramer
HOMOLOGY
interspecies homolog to murine Mat1a
Homologene
FAMILY
  • AdoMet synthetase family
    • CATEGORY enzyme , signaling
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • catalyzing a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine (AdoMet) which is the source of methyl groups for most biological methylations
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid
    signaling
    a component
  • complex of MATI (homotetramer of alpha 1 submit encoded by MAT1A)
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MAT1A
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS