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FLASH GENE
Symbol ARSF contributors: - updated : 16-05-2006
HGNC name arylsulfatase F
HGNC id 721
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 19 aa signal peptide (2.2 kda)
  • isoforms Precursor a 571 aa matude peptide (63.7 kda)
    HOMOLOGY
    intraspecies homolog to ARSC1
    Homologene
    FAMILY
  • sulfatase family
  • arylsulfatase subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    text
  • secreted
  • basic FUNCTION
  • playing an essential role for the correct composition of bone and cartilage matrix
  • acting as a sulfuric ester hydrolase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS ossification
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Ca2+ (a ion per subunit)
  • protein
    cell & other
    REGULATION
    inhibited by not inhibited by warfarin
    Other escaping inactivation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS