basic FUNCTION
| SCPx isoform is a peroxisomal thiolase cleaving 2-methyl branched chains mediating intracellular cholesterol in steroidogenic tissues |
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facilitates cholesterol (Ch) and phospholipid (PL) transfer/exchange between membranes and appears to play a key role in intracellular lipid trafficking |
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playing a role in intracellular phosphatidylinositol transfer, distribution, and signaling |
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enhances cholesterol retention within the cell as well as regulates the distribution of signaling lipids, such as phosphoinositides and sphingolipids, at plasma membrane caveolae |
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FABP1 and SCP2 facilitate the preferential movement of HDL-associated cholesteryl esters (HDL-CEs) to bile for final elimination |