Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | HGF | contributors: mct/npt - updated : 10-05-2017 |
HGNC name | hepatocyte growth factor (hepatopoietin A; scatter factor) |
HGNC id | 4893 |
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PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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secondary structure | pyrrolidone carboxylic acid (post translationally modified by the cyclization of a N-terminal glutamine) |
conjugated | GlycoP |
mono polymer | heteromer , dimer |
isoforms | Precursor | a 697 amino acids propetide (79,6 kda) |
HOMOLOGY |
interspecies | homolog to rattus Hgf (90,62 pc) |
homolog to murine Hgf (90,76 pc) |
Homologene |
FAMILY | |
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CATEGORY | signaling cytokine growth factor |
SUBCELLULAR LOCALIZATION | extracellular |
basic FUNCTION | |
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CELLULAR PROCESS | cell life, proliferation/growth |
cell communication | |
cell migration & motility |
PHYSIOLOGICAL PROCESS | development , nervous system |
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PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
repressed by | anti-tumor agent valproic acid (VPA), a histone deacetylase (HDAC) inhibitor |
ASSOCIATED DISORDERS |
corresponding disease(s) | DFNB39 |
Susceptibility |
Variant & Polymorphism SNP | HGF is a potential locus associated with high myopia in the Han Chinese population |
Candidate gene
Marker
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ANIMAL & CELL MODELS |