protein
| interacting with BBS4 |
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interacting with PIBF1 (both PIBF1 and PCM1 are required for ciliogenesis and are involved in the ciliary targeting of RAB8, a small GTPase shown to collaborate with BBS protein complex to promote ciliogenesis) |
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interaction between HOOK3 and PCM1 required by trafficking of pericentriolar satellites |
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interact directly with the disrupted-in-schizophrenia 1 (DISC1) protein, BBS4, and Huntingtin-associated protein 1, and is important in neuronal cell growth |
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HTT regulates ciliogenesis by interacting through HAP1 with pericentriolar material 1 protein (PCM1) |
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HOOK2 interacts with and stabilizes pericentriolar material protein 1 (PCM1), which was reported to be essential for the recruitment of RAB8A, a GTPase that is believed to be crucial for membrane transport to the primary cilium |
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CEP72 is a PCM1-interacting protein required for recruitment of the ciliopathy-associated protein CEP290 to centriolar satellites |
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CEP131 is recruited to centriolar satellites by PCM1, and localised to the centriolar core region by both pericentrin and CEP290 |
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PIBF1 physically interacts with PCM1 at centriolar satellites, and this interaction is essential for centrosomal accumulation of the centriolar satellites and eventually for primary cilia formation |
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centrin interactor POC5 leads to the assembly of linear, centrin-dependent structures that recruit other centrosomal proteins such as PCM1 and NEDD1 |
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MIB1 is a new component of centriolar satellites, which interacts with and ubiquitylates CEP131 and PCM1 and suppresses primary cilium formation |
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CCDC13 is a newly identified centriolar satellite protein that interacts with PCM1, CEP290 and pericentrin and prevents the accumulation of DNA damage during mitotic transit |
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SDCCAG8 interacts and cotraffics with pericentriolar material 1 (PCM1), a centriolar satellite protein crucial for targeting proteins to the centrosome |
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WRAP73 interacts with the satellite proteins SSX2IP and PCM1 as well as the centriolar proximal end component CEP135 |
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PLK4 interacts with the satellite component PCM1, and its kinase activity is required for phosphorylation of the conserved S372 |
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PCM1 is essential for tethering the E3 ligase, Mindbomb1 (MIB1), to satellites |