basic FUNCTION
| ATPase H+ transporting, non catalytic accessory protein, vacuolar proton pump 1 |
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in the epididymis and vas deferens, the vacuolar H(+)ATPase (V-ATPase), located in the apical pole of narrow and clear cells, is required to establish an acidic luminal pH and also participates in the acidification of intracellular organelles |
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ATP6V0A1, ATP6V0A2 cooperatively regulate the acidification and transmitter uptake/storage of dense-core vesicles, whereas they might not be as critical for exocytosis |