basic FUNCTION
| involved in the lens development and in the regulation of expression of eye lens cristallins |
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may be important in chondrocyte hypertrophy and terminal differentiation, and may be involved in the pathogenesis of osteoarthritis ![](pubmed.jpg) |
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required for the F4/80 expression in macrophages ![](pubmed.jpg) |
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implicated in transcriptional regulation of MMP13 |
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can significantly enhance MMP13 promoter activity via the AP-1 site ![](pubmed.jpg) |
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cellular counterpart of v-maf oncogene, that is a potent transactivator of the IL4 gene in Th2 cells ![](pubmed.jpg) |
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essential for the induction of IL10 by Tr1 (Type 1 regulatory T cells) ![](pubmed.jpg) |
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critical for glucagon gene transcription and alpha cell differentiation ![](pubmed.jpg) |
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act as key regulator of terminal differentiation in many tissues and organs, including bone, brain, kidney, lens, pancreas, and retina |
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is crucial for mechanosensory function ![](pubmed.jpg) |
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its ubiquitination is mediated by multiple lysine residues, of which K85 and K350 were sufficient but not the only residues in mediating MAF ubiquitination ![](pubmed.jpg) |