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FLASH GENE
Symbol PREP contributors: mct/npt - updated : 03-07-2008
HGNC name prolyl endopeptidase
HGNC id 9358
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • peptidase S9A family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    text also membrane-bound form in brain
    basic FUNCTION
  • prolyl oligopeptidase, serine endopeptidase activity
  • playing a role in movement regulation, cognition and possibly in inositol 1,4,5-triphosphate signaling
  • having a functions in axonal transport and/or protein secretion
  • participate in regulating the levels of seminal TRH analogues and in mediating sperm death associated with necrozoospermia
  • serine protease that cleaves small peptides at the carboxyl side of an internal proline residue
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS