basic FUNCTION
| involved in transcriptional regulation (Tommerup 1995) |
|
playing a role during development and organogenesis as well as in the function of the adult central nervous system (Trappe 2002) |
|
acting as a repressor of ESR1 signaling (Han 2008) |
|
is a transcriptional activator, a less common function of POZ-ZF proteins, that is negatively regulated by its heterodimerization partner ZBTB33 |
|
inhibits estrogen signaling by acting as an ESR1-co-repressor |
|
attenuates estrogen signaling by inhibiting ESR1 homo-dimerization |
|
required for Glioblastoma stem-like cell (GSC) viability, but dispensable for neural progenitor cell (NPC) viability |
|
ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5 |