Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GCLC | contributors: - updated : 25-11-2005 |
HGNC name | glutamate-cysteine ligase, catalytic subunit |
HGNC id | 4311 |
|
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| two subunits (heavy catalytic and light regulatory subunit) |
HOMOLOGY |
interspecies | homolog to murine Gclc |
Homologene |
FAMILY | glutamate cysteine ligase family 3 |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
two metal binding sites |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | GLCLC |
Susceptibility |
Variant & Polymorphism | association of polymorphism(-129C/T) with myocardial infarction |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |