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FLASH GENE
Symbol GMPR contributors: - updated : 18-06-2004
HGNC name guanosine monophosphate reductase
HGNC id 4376
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , tetramer
HOMOLOGY
interspecies homolog to rattus Gmpr
homolog to murine Gmpr
homolog to C.elegans F32d1.5
intraspecies homolog to GMPR2
Homologene
FAMILY IMPDH/GMPR family.
CATEGORY enzyme , immunity/defense
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • faciliting thermogenesis
  • functioning in the conversion of nucleoobase,nucleoside and nucleotide derivatives of G to A nucleotides
  • maintening the intracellular balance of A and G nucleotides
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    purine metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
    NADP
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS