basic FUNCTION
| TOR1AIP2 regulates the distribution and activity of TOR1A within the ER and NE lumen suggesting functional defects in the mutant protein responsible for DYT1 dystonia |
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endoplasmic reticulum membrane protein |
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TOR1AIP1, TOR1AIP2 regulate Torsin ATPase activity through an active site complementation mechanism |
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TOR1AIP2 is the most important component of the Torsin system with respect to viral production |
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oligomerizes likely to engage and transiently disassemble torsinA oligomers, and is thereby positioned to transduce cytoplasmic signals to the inner nuclear membrane (INM) through torsinA |
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might be an important molecule for maintaining genomic integrity and stability through upregulating or downregulating a cascade of genes to permit normal preimplantation embryo development |