basic FUNCTION
| novel histone H3K4 and H3K36 methyltransferase with transcriptional activation activity |
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plays an important role in the transcriptional regulation of muscle cell differentiation, by regulating muscle-specific factors, most notably myogenin, through interaction with MYOD1 |
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involved in a translocation to the immunoglobulin lambda light chain locus in one of the non-homologous end-joining/p53-deficient peripheral B cell lymphomas |
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exhibits histone methyltransferases activity on nucleosomal histone 3 in a SET-domain dependent manner |
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may play an important role in carcinogenesis |