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FLASH GENE
Symbol TCTN3 contributors: mct - updated : 25-08-2012
HGNC name tectonic family member 3
HGNC id 24519
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • necessary for transduction of the sonic hedgehog (SHH) signaling pathway
  • important for GLI3 processing and function, suggesting a complementary rather than redundant function for TCTN proteins in mammals
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) OFD4 , JBTS18
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS