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FLASH GENE
Symbol TMEM86B contributors: mct - updated : 23-04-2012
HGNC name transmembrane protein 86B
HGNC id 28449
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • many hydrophobic amino acids
  • six transmembrane domains
  • HOMOLOGY
    Homologene
    FAMILY YhhN family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic,microsome
    text located throughout the cytoplasm
    basic FUNCTION
  • catalyzes hydrolytic cleavage of the vinyl ether bond of lysoplasmalogen, forming fatty aldehyde and glycerophosphoethanolamine or glycerophosphocholine
  • may be important in regulating plasmalogen levels in animal cells
  • probably an important enzyme in maintaining the balance between plasmalogen and lysoplasmalogen and thereby preserving membrane stability and function
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS