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FLASH GENE
Symbol TIPRL contributors: mct/npt - updated : 25-11-2009
HGNC name TIP41 TOR signaling pathway regulator-like (S. cerevisiae)
HGNC id 30231
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • TIP41 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • inhibitory regulator of PP2A and implicate a role for TIP/PP2A complexes within the ATM/ATR signaling pathway controlling DNA replication and repair (McConnell 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • regulatory protein of PPP2R4 and the PP2A-like enzymes PPP4C and TMEM115 (interacts with the C-terminal region of the catalytic subunits of PPP2R4, PPP4C and TMEM115)(McConnell 2007)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS