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FLASH GENE
Symbol TMCO1 contributors: mct/npt - updated : 10-11-2014
HGNC name transmembrane and coiled-coil domains 1
HGNC id 18188
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • transmembrane and coiled-coil domains
  • HOMOLOGY
    Homologene
    FAMILY
  • TMCO1 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    intracellular,nucleus,nucleolus
    text
  • endogenous protein localizes to the cytoplasm and nucleus, and in the nucleus, the protein localizes to the nucleoli
  • basic FUNCTION
  • may have a critical role in early fetal growth and development (Yoda 2010)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CFSMR
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS