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FLASH GENE
Symbol NAA35 contributors: mct/npt - updated : 17-12-2018
HGNC name N(alpha)-acetyltransferase 35, NatC auxiliary subunit
HGNC id 24340
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • MAK10 family
  • CATEGORY enzyme , DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endosome
    basic FUNCTION
  • potential role for this gene in epithelial development, differentiation
  • essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development (Wenzlau 2006)
  • NATc-mediated N-terminal acetylation is important for maintenance of protein function and cell viability in human cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of NATc complex with NAA30 and NAA38
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS