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FLASH GENE
Symbol SKOR2 contributors: mct - updated : 19-03-2009
HGNC name SKI family transcriptional corepressor 2
HGNC id 32695
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
  • Ski/Sno proto-oncoproteins family
  • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • molecular regulator of BMP signaling
  • Smad-binding protein with a highly restricted expression pattern within the nervous system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with SMAD2, SMAD3 and SMAD4 and has an inhibitory activity on TGF-beta signaling
  • cell & other
    REGULATION
    PHYSICAL PROPERTIES fibrous
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    CELLULAR PROCESS nucleotide, repair, base excision repair
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker a specific marker for PCs in the cerebellum from their emergence until the adult stage
    Therapy target
    ANIMAL & CELL MODELS