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FLASH GENE
Symbol INCA1 contributors: mct - updated : 04-03-2009
HGNC name inhibitor of CDK, cyclin A1 interacting protein 1
HGNC id 32224
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • INCA family
  • CATEGORY signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text C9orf9 and INCA1 were found to be co-localized principally in the cytoplasm
    basic FUNCTION
  • plays a role in several signaling pathways important for cell cycle control and meiosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • substrates for the cyclin A1-CDK2 kinase complex
  • interaction between C9orf9 and INCA1
  • ING5 is a growth suppressor with suppressed expression in AML whose functions depend on its interaction with INCA1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS