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FLASH GENE
Symbol ADAT3 contributors: mct/npt - updated : 26-06-2008
HGNC name adenosine deaminase, tRNA-specific 3, TAD3 homolog (S. cerevisiae)
HGNC id 25151
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
interspecies homolog to S. Cerevisiae Tad3
Homologene
FAMILY
  • cytidine and deoxycytidylate deaminase family
  • ADAT3 subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in inosine formation in tRNAs
  • with ADAT2 function as a heterodimer which catalyses inosine formation at the wobble position (position 34) in eukaryotic tRNAs
  • playing an essential role for cell viability, illustrating the biological importance of A-to-I editing at the wobble position of tRNA
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS