Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SCN7A contributors: mct - updated : 16-01-2008
HGNC name sodium channel, voltage-gated, type VII, alpha
HGNC id 10594
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four transmembrane domains of homology, each with six alpha helical membrane spanning segments, and two cytoplasmic loops
  • HOMOLOGY
    Homologene
    FAMILY sodium channel family
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in the integration of synaptic input in the CNS
  • mediates the voltage-dependent sodium ion permeability of excitable membranes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component protein constituent of membrane
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • DLG1 contributes to the stabilization of SCN7A at the plasma membrane
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorder
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS