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FLASH GENE
Symbol MON1B contributors: mct - updated : 21-10-2011
HGNC name MON1 homolog B (yeast)
HGNC id 25020
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • five PKC phosphorylation sites
  • six myristoylation sites
  • a CAMP phosphorylation site
  • fiveCK2 phosphorylation sites
  • a tyr phosphorylation site
  • HOMOLOGY
    interspecies ortholog to murine Mon1b (85 pc)
    intraspecies homolog to MON1A
    Homologene
    FAMILY SAND protein family
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • required for phagosome maturation
  • virally induced protein expressed in HSV-1-infected cells, that is capable of interacting with transcriptional regulator proteins
  • likely inhibits viral gene transcriptional elongation by interacting with Cyclin T2
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by in human fibroblasts induced by herpes simplex virus 1 binding
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS