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FLASH GENE
Symbol TSSK6 contributors: mct - updated : 14-09-2020
HGNC name testis-specific serine kinase 6
HGNC id 30410
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a protein kinase domain
HOMOLOGY
Homologene
FAMILY ser/thr protein kinase family, SNF1 subfamily
CATEGORY
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
text localized to the heads of elongating spermatids
basic FUNCTION
  • required for proper postmeiotic chromatin remodeling and male fertility, for sperm production and function
  • plays a role in DNA condensation during
    • postmeiotic chromatin remodeling
  • is a proacrosin-binding protein
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
    magnesium
    protein
  • interacts and has functional relationship to the regulatory protein SNF4
  • interacts also with SIP1
  • interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS