Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ADAT2 contributors: mct - updated : 17-09-2013
HGNC name adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae)
HGNC id 21172
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a AAA type ATPase domain
  • a bromodomain
  • HOMOLOGY
    Homologene
    FAMILY
  • cytidine and deoxycytidylate deaminase family
  • ADAT2 subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • acts potentially on upstream and basic cellular processes to enhance oncogenesis in a variety of unrelated cell types
  • controls chromatin dynamics, genome transcriptional activities and apoptotic cell response
  • its overexpression in somatic cells, by acting on basic properties of chromatin, may contribute to malignant transformation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS