Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CEP70 contributors: mct/npt/pgu - updated : 02-04-2010
HGNC name centrosomal protein 70kDa
HGNC id 29972
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a putative HDAC (histone deacetylase) interacting domain
    • HOMOLOGY
    Homologene
    FAMILY
  • protein kinase PKN/PRK1 family
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    text localizes to the centrosome throughout the cell cycle (centrosomal localization pattern is dependent on its interaction with TUBG1)
    basic FUNCTION
  • role in making the cilium and involved in determination of the length of the axoneme
  • plays a significant role in the organization of both preexisting and nascent microtubules in interphase cells
  • necessary for the organization and orientation of the bipolar spindle during mitosis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with TUBG1 to localize at the centrosome and is critical for mitotic spindle assembly
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS