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FLASH GENE
Symbol PCP2 contributors: mct - updated : 13-03-2024
HGNC name Purkinje cell protein 2
HGNC id 30209
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one GoLoco domain
HOMOLOGY
interspecies ortholog to murine Pcp2
Homologene
FAMILY GoLoco domain-containing family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION
text localized in dendrites of neurons
basic FUNCTION
  • may be playing a role in controlling the development and/or motor control function of Purkinje cells
  • is likely a guanine nucleotide dissociation inhibitor
  • PCP2 facilitates cation channels closure in the dark, shortens the rise time of the light response directly, and accelerates the decay time indirectly via the inhibitory network
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS