basic FUNCTION
| acting as a protein serine/threonine kinase |
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upon serum stimulation, phosphorylating CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase |
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may be involved in trafficking and/or processing of RNA |
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involved in the regulation of protein export from nucleus |
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functionally related to microtubule dynamics and axon development |
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may have a role in the developing nervous system and the adult brain |
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phosphorylates the spliceosome assembly factor |
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SF1 |
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essential for neurite outgrowth in cortical neurons, stimulates 3' untranslated region-dependent local translation in neuritic projections, a component of the molecular device modulating translation in RNA-transporting granules and may participate in RNA splicing |