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FLASH GENE
Symbol GPN3 contributors: mct - updated : 05-01-2013
HGNC name GPN-loop GTPase 3
HGNC id 30186
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Atpbd1c
Homologene
FAMILY
  • GPN-loop GTPase family
  • small GTPases family
  • CATEGORY enzyme , RNA associated
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • GPN1/GPN3 define a new family of small GTPases that are specialized for the transport of RNA polymerase II into the nucleus
  • plays a critical role in the nuclear accumulation of RNAP II, and this function explains potentially the relative importance of GPN3 in cell proliferation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    ATP binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS