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FLASH GENE
Symbol CEACAM19 contributors: npt - updated : 05-03-2010
HGNC name carcinoembryonic antigen-related cell adhesion molecule 19
HGNC id 31951
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Immunoglobulin-like (Ig-like) transmembrane domains, present in most of the CEA proteins
  • one highly conserved domain of eukaryotic translation initiation factors
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Ceacam19
    Homologene
    FAMILY
  • CEA multigene family
  • immunoglobulin superfamily
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    repressed by dexamethasone in BT-474 breast cancer cell lines
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in ovarian cancers which are clinically more aggressive
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS