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FLASH GENE
Symbol SMAGP contributors: npt/mct - updated : 20/11/2008
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • binding domains for the protein 4.1
  • the PDZ domain of MAGUK proteins
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    basic FUNCTION
  • involved in a scaffolding protein complex, and therefore participate in the epithelium organization or in subsequent functions
  • strongly promotes tumor progression
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in breast, colon and lung cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS