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FLASH GENE

Symbol

DNTTIP2

contributors: - updated : 03-04-2006

HGNC name	deoxynucleotidyltransferase, terminal, interacting protein 2
HGNC id	24013

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	two ESR1 binding regions
	C-terminal ESR1 binding region is increased by estrogen while the binding of ERBP region at N-terminus is not affected by estrogen

HOMOLOGY

Homologene

FAMILY

CATEGORY

receptor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

enhancing the transcriptional activity of ESR1

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	bound to PPARG, RXRA, and ESR2
	interacting with the DNA binding domain and the hinge region of ESR1

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS