SUBCELLULAR LOCALIZATION
| plasma membrane,junction
|
| intracellular
|
| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endoplasmic reticulum
|
| intracellular,cytoplasm,organelle,Golgi
|
| intracellular,nucleus,nucleoplasm,nuclear bodies,PML
|
basic FUNCTION
| membrane-bound transcription regulator |
|
large cell surface glycoprotein with a single TMR found in all animal species |
|
play a role in development, neurite outgrowth, axon guidance, neuronal connectivity, and synaptogenesis |
|
requirement for Ten-m2 in the establishment of ipsilateral projections, and thus the generation of binocular circuits, critical for mammalian visual function |
|
TENM2 deficiency in human adipocyte precursors leads to induction of brown adipocyte marker genes upon adipogenic differentiation |