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FLASH GENE
Symbol PAAF1 contributors: npt - updated : 12-12-2005
HGNC name proteasomal ATPase-associated factor 1
HGNC id 25687
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • WD40 repeat domain
  • HOMOLOGY
    interspecies ortholog to chimpanzee LOC466705
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • functioning as a negative regulator of the proteasome by controling the assembly/disassembly of the proteasome
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    rheumatoid arthritis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS