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FLASH GENE
Symbol TANC1 contributors: npt/mct - updated : 04-02-2009
HGNC name tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
HGNC id 29364
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three tetratricopeptide repeats (TPRs)
  • ten ankyrin repeats
  • a coiled-coil region
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • working as a postsynaptic scaffold component by forming a multiprotein complex with various postsynaptic density proteins
  • scaffold protein that interacts with various postsynaptic scaffold and cytoskeletal proteins, including PSD-95 and SAP97)(Nonaka 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with TNIK and MINK1 (induced phosphorylation of TANC1)(Nonaka 2008)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS