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FLASH GENE
Symbol NACA2 contributors: npt - updated : 14-11-2006
HGNC name nascent polypeptide-associated complex alpha subunit 2
HGNC id 23290
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two N-glycosylation sites
  • several sites for protein phosphorylation
  • C-terminal fragment specifically binding IgE autoantibodies
  • secondary structure mostly of alpha helices and a single beta sheet
    HOMOLOGY
    interspecies ortholog to murine Naca
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • intracellular translocation of newly synthesized polypeptides
  • transcriptional coactivator
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component alpha-nascent polypeptide-associated complex
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
  • IgE autoantibodies
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS