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FLASH GENE
Symbol DNAJC11 contributors: mct - updated : 26-10-2007
HGNC name DnaJ (Hsp40) homolog, subfamily C, member 11
HGNC id 25570
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a DnaJ domain
  • a bipartite NLS
  • a FADH domain
  • a FEMCA domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY tumor suppressor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION candidate tumor suppressor genes of neuroblastoma
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein association with six other proteins, metaxins 1, and 2, CHCHD3, CHCHD6 and SAMM50, IMMT (putative role in protein import related to maintenance of mitochondrial structure)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral somatic mutation      
    in neuroblastoma (Henrich 2007)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS