SUBCELLULAR LOCALIZATION
| plasma membrane
|
| intracellular
|
| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,Golgi
|
| intracellular,cytoplasm,cytosolic,microsome
|
text
| type I membrane protein |
|
Golgi-derived coatomer-coated vesicles |
|
crucial constituent of the Golgi apparatus, associates with F2RL1 at the Golgi apparatus |
basic FUNCTION
| could have a role in the budding of coatomer-coated and other species of coated vesicles |
|
could bind cargo molecules to collect them into budding vesicles |
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inhibiting the GTPase-activating activity of ARFGAP1 |
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involved in vesicular targeting |
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cargo receptor facilitating calcium sensing receptor maturation and stabilization in the early secretory pathway |
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TMED2, TMED10 are specific cargo receptors of GPCRs and differentially control GPCR trafficking in the biosynthetic pathway, and thereby, TMED2 and TMED10 regulate GPCR signaling in astrocytes |
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required for transport of proteins between the endoplasmic reticulum and the Golgi |
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may play a role during placental development |