basic FUNCTION
| mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect |
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is a molecule with inhibitory effects on cell-mediated immune reactions |
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is crucial for maintaining the integrity of spindle poles during mitosis |
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likely PIBF1 affects the expression of leptin and its receptor, and PIBF1 expression is inversely related to trophoblast invasiveness |
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is a centriolar satellite protein that is critical for spindle pole integrity in mitotic cells |
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KISS1, KISS1R play a major role in trophoblast invasion, and progesterone-induced blocking factor (PIBF1) is needed for maintaining pregnancy |
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is an immunomodulatory protein with known role in the regulation of the immune response in the reproductive system |
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vital regulatory cascade involving IL33, decidual B cells and PIBF1 in safeguarding term pregnancy |
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promotes likely proliferation, migration, and invasion of human glioblastoma cells |