basic FUNCTION
| acting as a potassium channel |
|
may set the resting membrane potential of cells in the spinal cord |
|
key role in controlling neuronal resting membrane potential and neuronal excitability |
|
target of volatile anesthetics and potential role in mediating the effects of inhaled anesthetics in the central nervous system |
|
activation of both KCNK18 and NFAT via Ca(2+)-calcineurin-NFAT/KCNK18 pathway could modulate the transcription of new genes in addition to regulating several aspects of T-cell function |
|
role in the pathogenesis of typical migraine with aura |
|
plays an key part in the excitability of neurons that are crucial to migraine pathogenesis |