motifs/domains
| a gamma-carboxy-glutamate domain (Gla) domain, extracellular gamma-carboxyglutamic acid (Gla) protein domain |
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nine potential Gla residues (Gla residues are produced after subsequent posttranslational modifications of glutamate by a vitamin K-dependent gamma- carboxylase) |
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membrane-spanning hydrophobic regions |
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cytoplasmic C- terminal regions containing PPXY motifs |
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cytosolic WW binding motifs, essential for these newly found protein-protein interactions, and SH3 binding motifs, with a A PPXY WW domain binding motif present in the PRRG4 sequence at AAs 204–207 |