basic FUNCTION
| transporter activity |
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responsible for the uptake or efflux of adenine nucleotides into or from mitochondria and hence for the variation in the matrix adenine nucleotide content (which changes in physiopathological situations) |
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play an important role in modulating cell-death pathways by influencing the opening of the mPT pore through regulation of the calcium-buffering capacity of mitochondria and regulation of the total mitochondrial adenine content |
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exerts a negative feedback control between cellular Ca(2+) overload and mitochondrial permeability transition (mPT)-dependent cell death |
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importance of SLC25A24 in the regulation of body fat mass and adipogenesis |
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responsible for transporting ATP across the mitochondrial inner membrane |
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function of SLC25A24 is important for mitochondrial activities that depend on adenine nucleotides, such as gluconeogenesis and mitochondrial biogenesis |
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encodes a mitochondrial inner membrane ATP-Mg/Pi carrier |
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allows an electro-neutral and reversible exchange of ATP-Mg and phosphate between the cytosol and mitochondria, which is required for maintaining optimal adenine nucleotide levels in the mitochondrial matrix |