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FLASH GENE
Symbol CHPF contributors: mct/npt - updated : 22-04-2009
HGNC name chondroitin polymerizing factor
HGNC id 24291
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a domain containing beta 3-glycosyltransferase motif but lacked a typical beta 4-glycosyltransferase motif, which is the same as chondroitin sulfate glucuronyltransferase
    • HOMOLOGY
    Homologene
    FAMILY
  • chondroitin N-acetylgalactosaminyltransferase family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    text typical type II membrane protein
    basic FUNCTION
  • required for chondroitin polymerizing activity of chondroitin synthase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interactions between any two of CHSY1, CHSY3 and CHPF (co-expression of CHSY1 with CHPF resulted in a marked augmentation of glycosyltransferase activities and the expression of the chondroitin polymerase activity of HSY1)Izumikawa 2007)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS