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FLASH GENE
Symbol MAGEE1 contributors: mct - updated : 19-05-2020
HGNC name melanoma antigen family E, 1
HGNC id 24934
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a potential nuclear localization signal
  • 30 12-amino acid repeats
  • two MAGE homology domains
  • HOMOLOGY
    interspecies ortholog to murine Magee1
    Homologene
    FAMILY
  • MAGE family
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,nucleus
    intracellular,nuclear envelope
    basic FUNCTION
  • may play a signaling role in brain, muscle, and peripheral nerve
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • MAGEE1 associates directly with alpha-dystrobrevin (DTNA)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveliver
    may provide a promising therapeutic strategy for HCC treatment
    ANIMAL & CELL MODELS